| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RNA 3 terminal phosphate cyclase (317-366 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RTCA |
| Gene ID: |
8634 |
| Uniprot ID: |
RTCA_HUMAN |
| Immunogen Region: |
317-366 aa |
| Specificity: |
RTCD1 Polyclonal Antibody detects endogenous levels of RTCD1 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human RTCD1 at the amino acid range 317-366 |
| Function | Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP.(B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A.(C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. Likely functions in some aspects of cellular RNA processing. Function plays an important role in regulating axon regeneration by inhibiting central nervous system (CNS) axon regeneration following optic nerve injury. |
| Protein Name | Rna 3'-Terminal Phosphate CyclaseRna CyclaseRna-3'-Phosphate CyclaseRna Terminal Phosphate Cyclase Domain-Containing Protein 1Rtc Domain-Containing Protein 1 |
| Cellular Localisation | NucleusNucleoplasm |
| Alternative Antibody Names | Anti-Rna 3'-Terminal Phosphate Cyclase antibodyAnti-Rna Cyclase antibodyAnti-Rna-3'-Phosphate Cyclase antibodyAnti-Rna Terminal Phosphate Cyclase Domain-Containing Protein 1 antibodyAnti-Rtc Domain-Containing Protein 1 antibodyAnti-RTCA antibodyAnti-RPC antibodyAnti-RPC1 antibodyAnti-RTC1 antibodyAnti-RTCD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
