• Immunohistochemistry analysis of paraffin-embedded human brain tissue, using RPS19BP1 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-RPS19BP1 antibody (71-120 aa) (STJ95492)

SKU:
STJ95492

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Active regulator of SIRT1 (71-120 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RPS19BP1
Gene ID: 91582
Uniprot ID: AROS_HUMAN
Immunogen Region: 71-120 aa
Specificity: Ribosomal Protein S19BP Polyclonal Antibody detects endogenous levels of Ribosomal Protein S19BP protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human RPS19BP1 at the amino acid range 71-120
Post Translational Modifications Citrullinated by PADI4.
Function Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Acts as a chaperone that specifically mediates the integration of RPS19 in state post-A1. Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity.
Protein Name Active Regulator Of Sirt1
40s Ribosomal Protein S19-Binding Protein 1
Rps19-Binding Protein 1
S19bp
Database Links Reactome: R-HSA-3371453
Cellular Localisation Nucleus
Nucleolus
Alternative Antibody Names Anti-Active Regulator Of Sirt1 antibody
Anti-40s Ribosomal Protein S19-Binding Protein 1 antibody
Anti-Rps19-Binding Protein 1 antibody
Anti-S19bp antibody
Anti-RPS19BP1 antibody
Anti-AROS antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance