Anti-RPL23A antibody (17-67) (STJA0006334)

SKU:
STJA0006334
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Large ribosomal subunit protein uL23 (17-67) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:1000-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:RPL23A
Gene ID:6147
Uniprot ID:RL23A_HUMAN
Immunogen:Synthesized peptide derived from human RL23A AA range: 17-67
Immunogen Region:17-67
Specificity:This antibody detects endogenous levels of human RL23A
Function Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination.
Protein Name Large Ribosomal Subunit Protein Ul23
60s Ribosomal Protein L23a
Database Links Reactome: R-HSA-156827
Reactome: R-HSA-156902
Reactome: R-HSA-1799339
Reactome: R-HSA-192823
Reactome: R-HSA-2408557
Reactome: R-HSA-6791226
Reactome: R-HSA-72689
Reactome: R-HSA-72706
Reactome: R-HSA-72764
Reactome: R-HSA-9010553
Reactome: R-HSA-9633012
Reactome: R-HSA-975956
Reactome: R-HSA-975957
Cellular Localisation Cytoplasm
Nucleus
Although Rpl23a Is Functional Within The Cytoplasm
The Assembly Of Ribosomal Subunits Occurs In The Nucleus
Rpl23a Nuclear Import Is Mediated By Ipo5/Ranbp5
Ipo7/Ranbp7
Kpnb1/Importin-Beta Or Tpno1/Trn
Alternative Antibody Names Anti-Large Ribosomal Subunit Protein Ul23 antibody
Anti-60s Ribosomal Protein L23a antibody
Anti-RPL23A antibody

Information sourced from Uniprot.org