Anti-RPH3AL antibody (161-315) (STJ26615)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ26615
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General Information

Short DescriptionRabbit polyclonal RPH3AL (161-315) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF/ICC/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolRPH3AL
Gene ID9501
Uniprot IDRPH3L_HUMAN
Immunogen Region161-315
Immunogen SequenceKYILPLKTPGRADDPHFRPL PTEPAEREPRSSETSRIYTW ARGRVVSSDSDSDSDLSSSS LEDRLPSTGVRDRKGDKPWK ESGGSVEAPRMGFTHPPGHL SGCQSSLASGETGTGSADPP GGPRPGLTRRAPVKDTPGRA PAADAAPAGPSSCLG
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 161-315 of human RPH3AL (NP_008918.1).

Additional Info

Tissue Specificity Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
Function Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Acts as a potential RAB3B effector protein in epithelial cells.
Protein Name Rab Effector Noc2
No C2 Domains Protein
Rabphilin-3a-Like Protein
Database Links
Cellular Localisation Cytoplasm
Cytoplasmic Vesicle
Secretory Vesicle Membrane
Recruited To The Vesicle Membrane In A Gtp- And Rab3b-Dependent Manner In Epithelial Cells
Alternative Antibody Names Anti-Rab Effector Noc2 antibody
Anti-No C2 Domains Protein antibody
Anti-Rabphilin-3a-Like Protein antibody
Anti-RPH3AL antibody
Anti-NOC2 antibody

Information sourced from Uniprot.org

Citations

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