• STJ71282 (0. 3µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-RPGRIP1L antibody (Internal) (STJ71282)

SKU:
STJ71282-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-RPGRIP1L (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.3-1µg/ml
ELISA-antibody detection limit dilution 1:64000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: RPGRIP1L
Gene ID: 23322
Uniprot ID: FTM_HUMAN
Immunogen Region: Internal
Accession Number: NP_056087.2
Immunogen Sequence: DKENNKAKRDILK
Function Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis. Involved in the organization of apical junctions.the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis. Involved in establishment of planar cell polarity such as in cochlear sensory epithelium and is proposed to implicate stabilization of disheveled proteins. Involved in regulation of proteasomal activity at the primary cilium probably implicating association with PSDM2.
Protein Name Protein Fantom
Nephrocystin-8
Rpgr-Interacting Protein 1-Like Protein
Rpgrip1-Like Protein
Database Links Reactome: R-HSA-5610787
Reactome: R-HSA-5620912
Cellular Localisation Cytoplasm
Cytoskeleton
Cilium Basal Body
Cilium Axoneme
Microtubule Organizing Center
Centrosome
Cell Junction
Tight Junction
In Cultured Renal Cells
It Localizes Diffusely In The Cytoplasm But
As Cells Approach Confluence
It Accumulates To Basolateral Tight Junctions
Localizes To The Ciliary Transition Zone
Alternative Antibody Names Anti-Protein Fantom antibody
Anti-Nephrocystin-8 antibody
Anti-Rpgr-Interacting Protein 1-Like Protein antibody
Anti-Rpgrip1-Like Protein antibody
Anti-RPGRIP1L antibody
Anti-FTM antibody
Anti-KIAA1005 antibody
Anti-NPHP8 antibody

Information sourced from Uniprot.org

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