Anti-ROR2 antibody (900-943) {Biotin} (STJ502829)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 900-943on human ROR2 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-ROR2 (900-943) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Monkey/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.55-0.75 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:150 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ROR2 |
| Gene ID | 4920 |
| Uniprot ID | ROR2_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 900-943on human ROR2 protein. |
| Immunogen Region | 900-943 |
Additional Info
| Function | Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. |
| Protein Name | Tyrosine-Protein Kinase Transmembrane Receptor Ror2Neurotrophic Tyrosine Kinase - Receptor-Related 2 |
| Database Links | Reactome: R-HSA-4086400Reactome: R-HSA-5140745 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Transmembrane Receptor Ror2 antibodyAnti-Neurotrophic Tyrosine Kinase - Receptor-Related 2 antibodyAnti-ROR2 antibodyAnti-NTRKR2 antibody |
Information sourced from Uniprot.org