Anti-RNF219 antibody (600 aa) (STJ11107510)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RNF219 (600 aa) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OBI1 |
| Gene ID | 79596 |
| Uniprot ID | OBI1_HUMAN |
| Immunogen Region | 600 aa |
| Immunogen Sequence | QLENGSEWKPTSFFLLSPSD QEMNEDFSLHSSSCPVTNEI KPPSCLFQTEFSQGILLSSS HRLFEDQRFGSSLFKMSSEM HSLHNHLQSPWSTSFVPEKR NKNVNQSTKRKIQSSLSSAS PSKATKS |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 600 to the C-terminus of human RNF219 (NP_078822.3). |
Additional Info
| Post Translational Modifications | Auto-ubiquitinated. |
| Function | E3 ubiquitin ligase essential for DNA replication origin activation during S phase. Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase. |
| Protein Name | Orc Ubiquitin Ligase 1Obi1Ring Finger Protein 219 |
| Database Links | |
| Cellular Localisation | ChromosomeAssociation To Chromatin Is Cell Cycle-RegulatedAbsent From Mitotic ChromosomesIs Associated With Chromatin From G1 And Partially Released From Chromatin From Mid S-Phase |
| Alternative Antibody Names | Anti-Orc Ubiquitin Ligase 1 antibodyAnti-Obi1 antibodyAnti-Ring Finger Protein 219 antibodyAnti-OBI1 antibodyAnti-C13orf7 antibodyAnti-RNF219 antibody |
Information sourced from Uniprot.org