Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-RNF144A (52-179) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RNF144A |
Gene ID: |
9781 |
Uniprot ID: |
R144A_HUMAN |
Immunogen Region: |
52-179 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 52-179 of human RNF144A (NP_055561.2). |
Immunogen Sequence: |
ELLIKEGLETAISCPDAACP KQGHLQENEIECMVAAEIMQ RYKKLQFEREVLFDPCRTWC PASTCQAVCQLQDVGLQTPQ PVQCKACRMEFCSTCKASWH PGQGCPETMPITFLPGETSA AFKMEEDD |
Post Translational Modifications | Autoubiquitinated. |
Function | E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC. |
Protein Name | E3 Ubiquitin-Protein Ligase Rnf144aRing Finger Protein 144aUbcm4-Interacting Protein 4Ubiquitin-Conjugating Enzyme 7-Interacting Protein 4 |
Database Links | Reactome: R-HSA-8866654 |
Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinCytoplasmic Vesicle Membrane |
Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Rnf144a antibodyAnti-Ring Finger Protein 144a antibodyAnti-Ubcm4-Interacting Protein 4 antibodyAnti-Ubiquitin-Conjugating Enzyme 7-Interacting Protein 4 antibodyAnti-RNF144A antibodyAnti-KIAA0161 antibodyAnti-RNF144 antibodyAnti-UBCE7IP4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance