| Short Description : | Rabbit polyclonal anti-Ribonuclease 7 (37-87 aa) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RNASE7 |
| Gene ID: | 84659 |
| Uniprot ID: | RNAS7_HUMAN |
| Immunogen: | Synthesized peptide derived from the human RNAS7 at the amino acid range 37-87 |
| Immunogen Region: | 37-87 aa |
| Specificity: | This antibody detects endogenous levels of RNAS7 at Human |
| Function | Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. |
| Protein Name | Ribonuclease 7Rnase 7Skin-Derived Antimicrobial Protein 2Sap-2 |
| Database Links | Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedDetected In Urine |
| Alternative Antibody Names | Anti-Ribonuclease 7 antibodyAnti-Rnase 7 antibodyAnti-Skin-Derived Antimicrobial Protein 2 antibodyAnti-Sap-2 antibodyAnti-RNASE7 antibodyAnti-UNQ2516 antibodyAnti-PRO6006 antibody |
Information sourced from Uniprot.org
