• Western blot analysis of various lysates using RNASE3 Rabbit polyclonal antibody (STJ116699) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.

Anti-RNASE3 antibody (100-160) (STJ116699)

SKU:
STJ116699

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Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RNASE3 (100-160) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RNASE3
Gene ID: 6037
Uniprot ID: ECP_HUMAN
Immunogen Region: 100-160
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-160 of human RNASE3 (NP_002926.2).
Immunogen Sequence: RSRFRVPLLHCDLINPGAQN ISNCTYADRPGRRFYVVACD NRDPRDSPRYPVVPVHLDTT I
Function Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Protein Name Eosinophil Cationic Protein
Ecp
Ribonuclease 3
Rnase 3
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-6803157
Cellular Localisation Secreted
Located In The Matrix Of Eosinophil Large Specific Granule
Which Are Released Following Activation By An Immune Stimulus
Alternative Antibody Names Anti-Eosinophil Cationic Protein antibody
Anti-Ecp antibody
Anti-Ribonuclease 3 antibody
Anti-Rnase 3 antibody
Anti-RNASE3 antibody
Anti-ECP antibody
Anti-RNS3 antibody

Information sourced from Uniprot.org

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