| Host: |
Rabbit |
| Applications: |
WB/ELISA/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GTP-binding protein Rit1 (170-219 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RIT1 |
| Gene ID: |
6016 |
| Uniprot ID: |
RIT1_HUMAN |
| Immunogen Region: |
170-219 aa |
| Specificity: |
Rit1 Polyclonal Antibody detects endogenous levels of Rit1 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human RIT1 at the amino acid range 170-219 |
| Function | Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation. |
| Protein Name | Gtp-Binding Protein Rit1Ras-Like Protein Expressed In Many TissuesRas-Like Without Caax Protein 1 |
| Database Links | Reactome: R-HSA-187706 |
| Cellular Localisation | Cell Membrane |
| Alternative Antibody Names | Anti-Gtp-Binding Protein Rit1 antibodyAnti-Ras-Like Protein Expressed In Many Tissues antibodyAnti-Ras-Like Without Caax Protein 1 antibodyAnti-RIT1 antibodyAnti-RIBB antibodyAnti-RIT antibodyAnti-ROC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
