| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RHOT2 |
| Gene ID: | 89941 |
| Uniprot ID: | MIRO2_HUMAN |
| Immunogen Region: | 340-550 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 340-550 of human RHOT2 (NP_620124.1). |
| Immunogen Sequence: | PWGPELPRTVRTEAGRLPLH GYLCQWTLVTYLDVRSCLGH LGYLGYPTLCEQDQAHAITV TREKRLDQEKGQTQRSVLLC KVVGARGVGKSAFLQAFLGR GLGHQDTREQPPGYAIDTVQ VNGQEKYLILCEVGTDGLLA TSLDATCDVACLMFDGSDPK SFAHCASVYKHHYMDGQTPC LFVSSKADLPEGVAVSGPSP AEFCRKHRLPA |
| Tissue Specificity | Ubiquitously expressed. Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. |
| Post Translational Modifications | Ubiquitinated by PRKN in a PINK1-dependent manner, leading to its degradation. |
| Function | Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. |
| Protein Name | Mitochondrial Rho Gtpase 2Miro-2Hmiro-2Ras Homolog Gene Family Member T2 |
| Database Links | Reactome: R-HSA-9013419 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinColocalizes With Mgarp And Rhot2 At The Mitochondria |
| Alternative Antibody Names | Anti-Mitochondrial Rho Gtpase 2 antibodyAnti-Miro-2 antibodyAnti-Hmiro-2 antibodyAnti-Ras Homolog Gene Family Member T2 antibodyAnti-RHOT2 antibodyAnti-ARHT2 antibodyAnti-C16orf39 antibody |
Information sourced from Uniprot.org