| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Mouse/Rat/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Rhophilin 2 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments gave an approx 35kDa band in Human Pancreas and Prostate lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in t |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | RHPN2 |
| Gene ID: | 85415 |
| Uniprot ID: | RHPN2_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_149094.3 |
| Immunogen Sequence: | TNKNRQKSAST |
| Function | Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity. |
| Protein Name | Rhophilin-276 Kda Rhob Effector ProteinGtp-Rho-Binding Protein 2P76rbe |
| Database Links | Reactome: R-HSA-5666185Reactome: R-HSA-8980692Reactome: R-HSA-9013026 |
| Cellular Localisation | CytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-Rhophilin-2 antibodyAnti-76 Kda Rhob Effector Protein antibodyAnti-Gtp-Rho-Binding Protein 2 antibodyAnti-P76rbe antibodyAnti-RHPN2 antibody |
Information sourced from Uniprot.org
