| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RGS16 (1-202) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RGS16 |
| Gene ID: |
6004 |
| Uniprot ID: |
RGS16_HUMAN |
| Immunogen Region: |
1-202 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human RGS16 (NP_002919.3). |
| Immunogen Sequence: |
MCRTLAAFPTTCLERAKEFK TRLGIFLHKSELGCDTGSTG KFEWGSKHSKENRNFSEDVL GWRESFDLLLSSKNGVAAFH AFLKTEFSEENLEFWLACEE FKKIRSATKLASRAHQIFEE FICSEAPKEVNIDHETHELT RMNLQTATATCFDAAQGKTR TLMEKDSYPRFLKSPAYRDL AAQASAASATLSSCSLDEPS HT |
| Tissue Specificity | Abundantly expressed in retina with lower levels of expression in most other tissues. |
| Post Translational Modifications | Palmitoylated on Cys-2 and/or Cys-12. Phosphorylated. Phosphorylation at Tyr-168 by EGFR enhances GTPase accelerating (GAP) activity toward GNAI1. |
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals. |
| Protein Name | Regulator Of G-Protein Signaling 16Rgs16A28-Rgs14pRetinal-Specific RgsRgs-RHrgs-RRetinally Abundant Regulator Of G-Protein Signaling |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594Reactome: R-HSA-418597 |
| Cellular Localisation | MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 16 antibodyAnti-Rgs16 antibodyAnti-A28-Rgs14p antibodyAnti-Retinal-Specific Rgs antibodyAnti-Rgs-R antibodyAnti-Hrgs-R antibodyAnti-Retinally Abundant Regulator Of G-Protein Signaling antibodyAnti-RGS16 antibodyAnti-RGSR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
