| Short Description : | Rabbit polyclonal anti-Regulator of G-protein signaling 12 (141-190 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RGS12 |
| Gene ID: | 6002 |
| Uniprot ID: | RGS12_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human RGS12 at the amino acid range 141-190 |
| Immunogen Region: | 141-190 aa |
| Specificity: | RGS12 Polyclonal Antibody detects endogenous levels of RGS12 protein. |
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Isoform 5: Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis. |
| Protein Name | Regulator Of G-Protein Signaling 12Rgs12 |
| Database Links | Reactome: R-HSA-418594 |
| Cellular Localisation | NucleusCytoplasmCell ProjectionDendriteSynapseIsoform 5: Nucleus MatrixAlso Localized To Discrete Nuclear Foci That Are Distinct From Sites Of Rna ProcessingPml Nuclear BodiesAnd Pcg Domains |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 12 antibodyAnti-Rgs12 antibodyAnti-RGS12 antibody |
Information sourced from Uniprot.org
