| Short Description : | Rabbit polyclonal RFX2 (295-450) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RFX2 |
| Gene ID: | 5990 |
| Uniprot ID: | RFX2_HUMAN |
| Immunogen Region: | 295-450 |
| Immunogen Sequence: | MHQKPRYRPAQKTDSLGDSG SHSGLHSTPEQTMAVQSQHH QQYIDVSHVFPEFPAPDLGS FLLQDGVTLHDVKALQLVYR RHCEATVDVVMNLQFHYIEK LWLSFWNSKASSSDGPTSLP ASDEDPEGAVLPKDKLISLC QCDPILRWMRSCDHIL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 295-450 of human RFX2 (NP_000626.2). |
| Function | Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene H1-6. |
| Protein Name | Dna-Binding Protein Rfx2Regulatory Factor X 2 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmMainly Expressed In The Nucleus And At Lower Level In Cytoplasm |
| Alternative Antibody Names | Anti-Dna-Binding Protein Rfx2 antibodyAnti-Regulatory Factor X 2 antibodyAnti-RFX2 antibody |
Information sourced from Uniprot.org
