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Anti-RFC1 antibody (1071-1120 aa) (STJ96750)

Western blot analysis of lysate from K562 cells, using RFC1 Antibody.
Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-uterus, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-uterus, antibody was diluted at 1:100
Western blot analysis of K562 cells using RFC1 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-RFC1 antibody (1071-1120 aa) (STJ96750)

SKU:

STJ96750

£46.00 - £226.00

Current Stock:

General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Replication factor C subunit 1 (1071-1120 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC-P 1:100-1:300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	RFC1
Gene ID:	5981
Uniprot ID:	RFC1_HUMAN
Immunogen Region:	1071-1120 aa
Specificity:	RFC1 Polyclonal Antibody detects endogenous levels of RFC1 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the C-terminal region of human RFC1 at the amino acid range 1071-1120

Function	The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA. Interacts with C-terminus of PCNA. 5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair.
Protein Name	Replication Factor C Subunit 1 Activator 1 140 Kda Subunit A1 140 Kda Subunit Activator 1 Large Subunit Activator 1 Subunit 1 Dna-Binding Protein Po-Ga Replication Factor C 140 Kda Subunit Rf-C 140 Kda Subunit Rfc140 Replication Factor C Large Subunit
Database Links	Reactome: R-HSA-110312 Reactome: R-HSA-110314 Reactome: R-HSA-110320 Reactome: R-HSA-174411 Reactome: R-HSA-5651801 Reactome: R-HSA-5655862 Reactome: R-HSA-5656121 Reactome: R-HSA-5656169 Reactome: R-HSA-5685942 Reactome: R-HSA-5696397 Reactome: R-HSA-5696400 Reactome: R-HSA-6782135 Reactome: R-HSA-6782210 Reactome: R-HSA-69091
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Replication Factor C Subunit 1 antibody Anti-Activator 1 140 Kda Subunit antibody Anti-A1 140 Kda Subunit antibody Anti-Activator 1 Large Subunit antibody Anti-Activator 1 Subunit 1 antibody Anti-Dna-Binding Protein Po-Ga antibody Anti-Replication Factor C 140 Kda Subunit antibody Anti-Rf-C 140 Kda Subunit antibody Anti-Rfc140 antibody Anti-Replication Factor C Large Subunit antibody Anti-RFC1 antibody Anti-RFC140 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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