| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Renin (250-406) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:100-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
REN |
| Gene ID: |
5972 |
| Uniprot ID: |
RENI_HUMAN |
| Immunogen Region: |
250-406 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 250-406 of human Renin (NP_000528.1). |
| Immunogen Sequence: |
QHYEGNFHYINLIKTGVWQI QMKGVSVGSSTLLCEDGCLA LVDTGASYISGSTSSIEKLM EALGAKKRLFDYVVKCNEGP TLPDISFHLGGKEYTLTSAD YVFQESYSSKKLCTLAIHAM DIPPPTGPTWALGATFIRKF YTEFDRRNNRIGFALAR |
| Function | Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| Protein Name | ReninAngiotensinogenase |
| Database Links | Reactome: R-HSA-2022377 |
| Cellular Localisation | SecretedMembraneAssociated To Membranes Via Binding To Atp6ap2 |
| Alternative Antibody Names | Anti-Renin antibodyAnti-Angiotensinogenase antibodyAnti-REN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
