Anti-REN antibody (250-406) (STJ25336)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Renin (250-406) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | REN |
| Gene ID | 5972 |
| Uniprot ID | RENI_HUMAN |
| Immunogen Region | 250-406 |
| Immunogen Sequence | QHYEGNFHYINLIKTGVWQI QMKGVSVGSSTLLCEDGCLA LVDTGASYISGSTSSIEKLM EALGAKKRLFDYVVKCNEGP TLPDISFHLGGKEYTLTSAD YVFQESYSSKKLCTLAIHAM DIPPPTGPTWALGATFIRKF YTEFDRRNNRIGFALAR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 250-406 of human Renin (NP_000528.1). |
Additional Info
| Function | Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| Protein Name | ReninAngiotensinogenase |
| Database Links | Reactome: R-HSA-2022377 |
| Cellular Localisation | SecretedMembraneAssociated To Membranes Via Binding To Atp6ap2 |
| Alternative Antibody Names | Anti-Renin antibodyAnti-Angiotensinogenase antibodyAnti-REN antibody |
Information sourced from Uniprot.org