Anti-Recombinant-WASF2 antibody [RM2P08] (STJA0026269)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Actin-Binding Protein Wasf2 for use in IF, IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2P08 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | WASF2 |
| Gene ID | 10163 |
| Uniprot ID | WASF2_HUMAN |
Additional Info
| Function | Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. |
| Protein Name | Actin-Binding Protein Wasf2Protein Wave-2Verprolin Homology Domain-Containing Protein 2Wiskott-Aldrich Syndrome Protein Family Member 2Wasp Family Protein Member 2 |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-4420097Reactome: R-HSA-5663213Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013423Reactome: R-HSA-9664422 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionLamellipodiumBasolateral Cell MembraneAt The Interface Between The Lamellipodial Actin Meshwork And The Membrane |
| Alternative Antibody Names | Anti-Actin-Binding Protein Wasf2 antibodyAnti-Protein Wave-2 antibodyAnti-Verprolin Homology Domain-Containing Protein 2 antibodyAnti-Wiskott-Aldrich Syndrome Protein Family Member 2 antibodyAnti-Wasp Family Protein Member 2 antibodyAnti-WASF2 antibodyAnti-WAVE2 antibody |
Information sourced from Uniprot.org