Host: | Rabbit |
Applications: | FC/IF/IP/WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-Recombinant-Proto-Oncogene Vav is suitable for use in Flow Cytometry, Immunofluorescence, Immunoprecipitation and Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | RM1P80 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.01M PBS |
Purification: | Protein A/G purified from cell culture supernatant |
Dilution Range: | FCM: 1:20-1:100 |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Post Translational Modifications | Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN. |
Function | Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. |
Protein Name | Proto-Oncogene Vav |
Database Links | Reactome: R-HSA-114604Reactome: R-HSA-1257604Reactome: R-HSA-1433557Reactome: R-HSA-193648Reactome: R-HSA-2029482Reactome: R-HSA-2219530Reactome: R-HSA-2871796Reactome: R-HSA-2871809Reactome: R-HSA-389359Reactome: R-HSA-416482Reactome: R-HSA-4420097Reactome: R-HSA-512988Reactome: R-HSA-5218920Reactome: R-HSA-6811558Reactome: R-HSA-8980692Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013408Reactome: R-HSA-9027284Reactome: R-HSA-912631Reactome: R-HSA-9664422Reactome: R-HSA-9679191Reactome: R-HSA-9748787Reactome: R-HSA-983695 |
Alternative Antibody Names | Anti-Proto-Oncogene Vav antibodyAnti-VAV1 antibodyAnti-VAV antibody |
Information sourced from Uniprot.org