Anti-Recombinant-LCP1 antibody [RM1P10] (STJA0023895)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Plastin-2 for use in IF, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1P10 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | LCP1 |
| Gene ID | 3936 |
| Uniprot ID | PLSL_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated on a serine residue in response to costimulation through TCR/CD3 and CD2 or CD28. Serine phosphorylation promotes association with the actin cytoskeleton and targeting to peripheral cell projections. |
| Function | Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. |
| Protein Name | Plastin-2L-PlastinLc64pLymphocyte Cytosolic Protein 1Lcp-1 |
| Database Links | Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionCell ProjectionRuffle MembranePeripheral Membrane ProteinCytoplasmic SideRelocalizes To The Immunological Synapse Between Peripheral Blood T-Lymphocytes And Antibody-Presenting Cells In Response To Costimulation Through Tcr/Cd3 And Cd2 Or Cd28Associated With The Actin Cytoskeleton At Membrane RufflesRelocalizes To Actin-Rich Cell Projections Upon Serine Phosphorylation |
| Alternative Antibody Names | Anti-Plastin-2 antibodyAnti-L-Plastin antibodyAnti-Lc64p antibodyAnti-Lymphocyte Cytosolic Protein 1 antibodyAnti-Lcp-1 antibodyAnti-LCP1 antibodyAnti-PLS2 antibody |
Information sourced from Uniprot.org