Anti-Recombinant-GMNN antibody [RM1F40] (STJA0023133)

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STJA0023133
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Geminin is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1F40
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: GMNN
Gene ID: 51053
Uniprot ID: GEMI_HUMAN
Function Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control.
Protein Name Geminin
Database Links Reactome: R-HSA-68867
Reactome: R-HSA-68962
Reactome: R-HSA-69052
Cellular Localisation Cytoplasm
Nucleus
Mainly Cytoplasmic But Can Be Relocalized To The Nucleus
Alternative Antibody Names Anti-Geminin antibody
Anti-GMNN antibody

Information sourced from Uniprot.org

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