| Host: | Rabbit |
| Applications: | FC/IF/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-Recombinant-Transcription Factor Etv6 is suitable for use in Flow Cytometry, Immunofluorescence and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | RM1V86 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | FCM: 1:20-1:100 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | ETV6 |
| Gene ID: | 2120 |
| Uniprot ID: | ETV6_HUMAN |
| Post Translational Modifications | Phosphorylation of Ser-257 by MAPK14 (p38) inhibits ETV6 transcriptional repression. |
| Function | Transcriptional repressor.binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation. |
| Protein Name | Transcription Factor Etv6Ets Translocation Variant 6Ets-Related Protein Tel1Tel |
| Database Links | Reactome: R-HSA-9673768Reactome: R-HSA-9703465 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Etv6 antibodyAnti-Ets Translocation Variant 6 antibodyAnti-Ets-Related Protein Tel1 antibodyAnti-Tel antibodyAnti-ETV6 antibodyAnti-TEL antibodyAnti-TEL1 antibody |
Information sourced from Uniprot.org
