| Function | Protease component of the ClpXP complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The ClpXP complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Cleaves PINK1 in the mitochondrion. |
| Protein Name | Atp-Dependent Clp Protease Proteolytic Subunit - MitochondrialCaseinolytic Mitochondrial Matrix Peptidase Proteolytic SubunitEndopeptidase Clp |
| Database Links | Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Atp-Dependent Clp Protease Proteolytic Subunit - Mitochondrial antibodyAnti-Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit antibodyAnti-Endopeptidase Clp antibodyAnti-CLPP antibody |
Information sourced from Uniprot.org
