| Host: | Chicken |
| Applications: | ICC/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Chicken monoclonal anti-Recombinant-Calretinin (1-178 N-Term) for use in ICC and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | L122/6 |
| Conjugation: | FL594 Ex: 594 nm, Em: 615 nm |
| Isotype: | IgY |
| Formulation: | 1X PBS, 0.05% Sodium Azide pH 7.4 |
| Purification: | Purified by affinity chromatography |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Aliquot and store at ≤-20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap. |
| Gene Symbol: | CALB2 |
| Gene ID: | 794 |
| Uniprot ID: | CALB2_HUMAN |
| Immunogen Region: | 1-178 N-Term |
| Specificity: | No cross-reactivity reported |
| Immunogen: | Fusion protein amino acids 1-178 (N-terminus) of human CALB2 (accession number) produced recombinantly in E. Coli |
| Immunogen Sequence: | Human |
| Tissue Specificity | Brain. |
| Function | Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways. Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory. During embryonic development, it facilitates neuronal differentiation and maturation. |
| Protein Name | CalretininCr29 Kda Calbindin |
| Database Links | |
| Cellular Localisation | SynapseCell ProjectionDendriteLocated In DendriolesSmall Dendrites That Makes Up A Brush Structure Found As The Terminal Specialization Of A Dendrite Of A Unipolar Brush Cell |
| Alternative Antibody Names | Anti-Calretinin antibodyAnti-Cr antibodyAnti-29 Kda Calbindin antibodyAnti-CALB2 antibodyAnti-CAB29 antibody |
Information sourced from Uniprot.org