Anti-RASA4 antibody (100-180 aa) (STJ191257)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 100-180
General Information
| Short Description | Rabbit polyclonal anti-Ras GTPase-activating protein 4 (100-180 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RASA4 |
| Gene ID | 10156 |
| Uniprot ID | RASL2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 100-180 |
| Immunogen Region | 100-180 aa |
| Specificity | RASL2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. |
| Protein Name | Ras Gtpase-Activating Protein 4Calcium-Promoted Ras InactivatorRas P21 Protein Activator 4Rasgap-Activating-Like Protein 2 |
| Database Links | Reactome: R-HSA-5658442 |
| Cellular Localisation | CytoplasmCytosolCell MembranePeripheral Membrane ProteinLocalized To The Cytosol As A Result Of Its Lack Of Phosphoinositide Binding ActivityUpon Agonist-Stimulated Calcium MobilizationUtilizes The C2a And C2b Domains To Associate With The Plasma Membrane |
| Alternative Antibody Names | Anti-Ras Gtpase-Activating Protein 4 antibodyAnti-Calcium-Promoted Ras Inactivator antibodyAnti-Ras P21 Protein Activator 4 antibodyAnti-Rasgap-Activating-Like Protein 2 antibodyAnti-RASA4 antibodyAnti-CAPRI antibodyAnti-GAPL antibodyAnti-KIAA0538 antibody |
Information sourced from Uniprot.org