| Short Description : | Rabbit polyclonal anti-Ras GTPase-activating protein 4 (100-180 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RASA4 |
| Gene ID: | 10156 |
| Uniprot ID: | RASL2_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 100-180 |
| Immunogen Region: | 100-180 aa |
| Specificity: | RASL2 Polyclonal Antibody detects endogenous levels of protein. |
| Function | Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. |
| Protein Name | Ras Gtpase-Activating Protein 4Calcium-Promoted Ras InactivatorRas P21 Protein Activator 4Rasgap-Activating-Like Protein 2 |
| Database Links | Reactome: R-HSA-5658442 |
| Cellular Localisation | CytoplasmCytosolCell MembranePeripheral Membrane ProteinLocalized To The Cytosol As A Result Of Its Lack Of Phosphoinositide Binding ActivityUpon Agonist-Stimulated Calcium MobilizationUtilizes The C2a And C2b Domains To Associate With The Plasma Membrane |
| Alternative Antibody Names | Anti-Ras Gtpase-Activating Protein 4 antibodyAnti-Calcium-Promoted Ras Inactivator antibodyAnti-Ras P21 Protein Activator 4 antibodyAnti-Rasgap-Activating-Like Protein 2 antibodyAnti-RASA4 antibodyAnti-CAPRI antibodyAnti-GAPL antibodyAnti-KIAA0538 antibody |
Information sourced from Uniprot.org
