• Western blot analysis of extracts from wild type (WT) and RARG knockdown (KD) MCF7 cells, using RARG antibody (STJ11104541) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
  • Western blot analysis of extracts of SK-BR-3 cells, using RARG antibody (STJ11104541) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-RARG antibody (1-70) (STJ11104541)

SKU:
STJ11104541

£129.50 - £639.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Retinoic Acid Receptor Gamma (1-70) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RARG
Gene ID: 5916
Uniprot ID: RARG_HUMAN
Immunogen Region: 1-70
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RARG (NP_000957.1).
Immunogen Sequence: MATNKERLFAAGALGPGSGY PGAGFPFAFPGALRGSPPFE MLSPSFRGLGQPDLPKEMAS LSVETQSTSS
Tissue Specificity Expressed in aortic endothelial cells (at protein level).
Function Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
Protein Name Retinoic Acid Receptor Gamma
Rar-Gamma
Nuclear Receptor Subfamily 1 Group B Member 3
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-5362517
Reactome: R-HSA-5617472
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Retinoic Acid Receptor Gamma antibody
Anti-Rar-Gamma antibody
Anti-Nuclear Receptor Subfamily 1 Group B Member 3 antibody
Anti-RARG antibody
Anti-NR1B3 antibody

Information sourced from Uniprot.org

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