| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S2MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAP1GAP |
| Gene ID: | 5909 |
| Uniprot ID: | RPGP1_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Rap1GAP (P47736). |
| Immunogen Sequence: | MIEKMQGSRMDEQRCSFPPP LKTEEDYIPYPSVHEVLGRE GPFPLILLPQFGGYWIEGTN HEITSIPETEPLQSPTTKVK LECNPTARIYRKHFLGKEHF |
| Tissue Specificity | Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues. |
| Function | GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. |
| Protein Name | Rap1 Gtpase-Activating Protein 1Rap1gapRap1gap1 |
| Database Links | Reactome: R-HSA-392517Reactome: R-HSA-8853659 |
| Cellular Localisation | Golgi Apparatus MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Rap1 Gtpase-Activating Protein 1 antibodyAnti-Rap1gap antibodyAnti-Rap1gap1 antibodyAnti-RAP1GAP antibodyAnti-KIAA0474 antibodyAnti-RAP1GA1 antibody |
Information sourced from Uniprot.org