Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-RAP1GAP (1-100) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Monoclonal |
Clone ID: | S2MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | RAP1GAP |
Gene ID: | 5909 |
Uniprot ID: | RPGP1_HUMAN |
Immunogen Region: | 1-100 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Rap1GAP (P47736). |
Immunogen Sequence: | MIEKMQGSRMDEQRCSFPPP LKTEEDYIPYPSVHEVLGRE GPFPLILLPQFGGYWIEGTN HEITSIPETEPLQSPTTKVK LECNPTARIYRKHFLGKEHF |
Tissue Specificity | Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues. |
Function | GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. |
Protein Name | Rap1 Gtpase-Activating Protein 1 Rap1gap Rap1gap1 |
Database Links | Reactome: R-HSA-392517 Reactome: R-HSA-8853659 |
Cellular Localisation | Golgi Apparatus Membrane Peripheral Membrane Protein |
Alternative Antibody Names | Anti-Rap1 Gtpase-Activating Protein 1 antibody Anti-Rap1gap antibody Anti-Rap1gap1 antibody Anti-RAP1GAP antibody Anti-KIAA0474 antibody Anti-RAP1GA1 antibody |
Information sourced from Uniprot.org