| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RALY |
| Gene ID: | 22913 |
| Uniprot ID: | RALY_HUMAN |
| Immunogen Region: | 96-306 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 96-306 of human RALY (NP_057951.1). |
| Immunogen Sequence: | DRPKGLKRAASAIYSGYIFD YDYYRDDFYDRLFDYRGRLS PVPVPRAVPVKRPRVTVPLV RRVKTNVPVKLFARSTAVTT SSAKIKLKSSELQAIKTELT QIKSNIDALLSRLEQIAAEQ KANPDGKKKGDGGGAGGGGG GGGSGGGGSGGGGGGGSSRP PAPQENTTSEAGLPQGEART RDDGDEEGLLTHSEEELEHS QDTDADDGALQ |
| Tissue Specificity | Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta. |
| Function | RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis. May be a heterogeneous nuclear ribonucleoprotein (hnRNP). |
| Protein Name | Rna-Binding Protein RalyAutoantigen P542Heterogeneous Nuclear Ribonucleoprotein C-Like 2Hnrnp Core Protein C-Like 2Hnrnp Associated With Lethal Yellow Protein Homolog |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Rna-Binding Protein Raly antibodyAnti-Autoantigen P542 antibodyAnti-Heterogeneous Nuclear Ribonucleoprotein C-Like 2 antibodyAnti-Hnrnp Core Protein C-Like 2 antibodyAnti-Hnrnp Associated With Lethal Yellow Protein Homolog antibodyAnti-RALY antibodyAnti-HNRPCL2 antibodyAnti-P542 antibody |
Information sourced from Uniprot.org