Anti-RALY antibody (96-306) (STJ11102735)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RALY (96-306) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RALY |
| Gene ID | 22913 |
| Uniprot ID | RALY_HUMAN |
| Immunogen Region | 96-306 |
| Immunogen Sequence | DRPKGLKRAASAIYSGYIFD YDYYRDDFYDRLFDYRGRLS PVPVPRAVPVKRPRVTVPLV RRVKTNVPVKLFARSTAVTT SSAKIKLKSSELQAIKTELT QIKSNIDALLSRLEQIAAEQ KANPDGKKKGDGGGAGGGGG GGGSGGGGSGGGGGGGSSRP PAPQENTTSEAGLPQGEART RDDGDEEGLLTHSEEELEHS QDTDADDGALQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 96-306 of human RALY (NP_057951.1). |
Additional Info
| Tissue Specificity | Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta. |
| Function | RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis. May be a heterogeneous nuclear ribonucleoprotein (hnRNP). |
| Protein Name | Rna-Binding Protein RalyAutoantigen P542Heterogeneous Nuclear Ribonucleoprotein C-Like 2Hnrnp Core Protein C-Like 2Hnrnp Associated With Lethal Yellow Protein Homolog |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Rna-Binding Protein Raly antibodyAnti-Autoantigen P542 antibodyAnti-Heterogeneous Nuclear Ribonucleoprotein C-Like 2 antibodyAnti-Hnrnp Core Protein C-Like 2 antibodyAnti-Hnrnp Associated With Lethal Yellow Protein Homolog antibodyAnti-RALY antibodyAnti-HNRPCL2 antibodyAnti-P542 antibody |
Information sourced from Uniprot.org