• Western blot analysis of lysates from PC-12 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-RABGEF1 antibody (291-341 aa) (STJ194178)

SKU:
STJ194178

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Rab5 GDP/GTP exchange factor (291-341 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RABGEF1
Gene ID: 27342
Uniprot ID: RABX5_HUMAN
Immunogen Region: 291-341 aa
Specificity: This antibody detects endogenous levels of RABX5 at Human/Mouse
Immunogen: Synthesized peptide derived from the human RABX5 at the amino acid range 291-341
Function Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
Protein Name Rab5 Gdp/Gtp Exchange Factor
Rap1
Rabaptin-5-Associated Exchange Factor For Rab5
Rabex-5
Database Links Reactome: R-HSA-8854214
Reactome: R-HSA-8876198
Cellular Localisation Cytoplasm
Early Endosome
Recycling Endosome
Alternative Antibody Names Anti-Rab5 Gdp/Gtp Exchange Factor antibody
Anti-Rap1 antibody
Anti-Rabaptin-5-Associated Exchange Factor For Rab5 antibody
Anti-Rabex-5 antibody
Anti-RABGEF1 antibody
Anti-RABEX5 antibody

Information sourced from Uniprot.org

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