Anti-RABAC1 antibody (1-185) (STJ11103179)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RABAC1 (1-185) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RABAC1 |
| Gene ID | 10567 |
| Uniprot ID | PRAF1_HUMAN |
| Immunogen Region | 1-185 |
| Immunogen Sequence | MAAQKDQQKDAEAEGLSGTT LLPKLIPSGAGREWLERRRA TIRPWSTFVDQQRFSRPRNL GELCQRLVRNVEYYQSNYVF VFLGLILYCVVTSPMLLVAL AVFFGACYILYLRTLESKLV LFGREVSPAHQYALAGGISF PFFWLAGAGSAVFWVLGATL VVIGSHAAFHQIEAVDGEEL QMEPV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human RABAC1 (NP_006414.2). |
Additional Info
| Tissue Specificity | Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach. |
| Function | General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI. |
| Protein Name | Prenylated Rab Acceptor Protein 1Pra1 Family Protein 1 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmGolgi ApparatusCytoplasmic VesicleSecretory VesicleSynaptic VesicleAccording To Some AuthorsIt Is An Integral Membrane ProteinWhile Others Showed That It Is Cytoplasmic And Membrane-Associated To Golgi And Synaptic Vesicles |
| Alternative Antibody Names | Anti-Prenylated Rab Acceptor Protein 1 antibodyAnti-Pra1 Family Protein 1 antibodyAnti-RABAC1 antibodyAnti-PRA1 antibodyAnti-PRAF1 antibody |
Information sourced from Uniprot.org