| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RABAC1 |
| Gene ID: | 10567 |
| Uniprot ID: | PRAF1_HUMAN |
| Immunogen Region: | 1-185 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human RABAC1 (NP_006414.2). |
| Immunogen Sequence: | MAAQKDQQKDAEAEGLSGTT LLPKLIPSGAGREWLERRRA TIRPWSTFVDQQRFSRPRNL GELCQRLVRNVEYYQSNYVF VFLGLILYCVVTSPMLLVAL AVFFGACYILYLRTLESKLV LFGREVSPAHQYALAGGISF PFFWLAGAGSAVFWVLGATL VVIGSHAAFHQIEAVDGEEL QMEPV |
| Tissue Specificity | Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach. |
| Function | General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI. |
| Protein Name | Prenylated Rab Acceptor Protein 1 Pra1 Family Protein 1 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cytoplasm Golgi Apparatus Cytoplasmic Vesicle Secretory Vesicle Synaptic Vesicle According To Some Authors It Is An Integral Membrane Protein While Others Showed That It Is Cytoplasmic And Membrane-Associated To Golgi And Synaptic Vesicles |
| Alternative Antibody Names | Anti-Prenylated Rab Acceptor Protein 1 antibody Anti-Pra1 Family Protein 1 antibody Anti-RABAC1 antibody Anti-PRA1 antibody Anti-PRAF1 antibody |
Information sourced from Uniprot.org
