| Host: | Goat |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat/Bovine/Canine/Chicken/Avian/Donkey/Feline/Goat/Guinea Pig/Hamster/Horse/Porcine/Rabbit/Sheep/Simian |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal anti-RAB9B, member RAS oncogene family (115aa C-Term) for use in WB in Human, Mouse, Rat, Bovine, Canine, Chicken, Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep and Simian samples. Datasheet included |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Purification: | This antibody is epitope-affinity purified from goat antiserum. |
| Concentration: | 3 mg/mL |
| Dilution Range: | WB 1:250-1:2000 |
| Storage Instruction: | Store at-20 C for long-term storage. Store at 2-8 C for up to one month. |
| Gene Symbol: | RAB9B |
| Gene ID: | 51209 |
| Uniprot ID: | RAB9B_HUMAN |
| Immunogen Region: | 115aa C-Term |
| Accession Number: | ENSG00000123570 |
| Specificity: | Rab9b antibody detects endogenous levels of Rab9b protein (brain) and transfected cells with GFP-Rab9b cds. This antibody does not recognize Rab9a. |
| Immunogen: | Purified recombinant peptide derived from within residues 115 aa to the C-terminus of Rab9b produced in E. coli. |
| Immunogen Sequence: | EFMDPDHFPFVVLGNKVDKE FMDPDHFPFVVLGNKVDKED MDPDHFPFVVLGNKVDKEDR DPDHFPFVVLGNKVDKEDRQ PDHFPFVVLGNKVDKEDRQV |
| Tissue Specificity | Ubiquitous. |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB9B is involved in the transport of proteins between the endosomes and the trans Golgi network. May use NDE1/NDEL1 as an effector to interact with the dynein motor complex in order to control retrograde trafficking of RAB9-associated late endosomes to the TGN. |
| Protein Name | Ras-Related Protein Rab-9bRab-9-Like ProteinRab-9l |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6811440Reactome: R-HSA-8873719Reactome: R-HSA-8876198Reactome: R-HSA-9706019 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideCytoplasmic VesiclePhagosomePhagosome MembraneRecruited To Phagosomes Containing SAureus Or MTuberculosis |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-9b antibodyAnti-Rab-9-Like Protein antibodyAnti-Rab-9l antibodyAnti-RAB9B antibodyAnti-RAB9L antibody |
Information sourced from Uniprot.org
