| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | QSOX2 |
| Gene ID: | 169714 |
| Uniprot ID: | QSOX2_HUMAN |
| Immunogen Region: | 370-650 |
| Immunogen Sequence: | VKKLLEMLQEWLASLPLDRI PYNAVLDLVNNKMRISGIFL TNHIKWVGCQGSRSELRGYP CSLWKLFHTLTVEASTHPDA LVGTGFEDDPQAVLQTMRRY VHTFFGCKECGEHFEEMAKE SMDSVKTPDQAILWLWKKHN MVNGRLAGHLSEDPRFPKLQ WPTPDLCPACHEEIKGLASW DEGHVLTFLKQHYGRDNLLD TYSADQGDSSEGGTLARGEE EEKRLTPPEVSHGDRDTQS |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 370-650 of human QSOX2 (NP_859052.3). |
| Tissue Specificity | Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles. |
| Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis. |
| Protein Name | Sulfhydryl Oxidase 2Neuroblastoma-Derived Sulfhydryl OxidaseQuiescin Q6-Like Protein 1 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinSecretedCell MembraneNucleus MembraneSeems To Be Predominantly Targeted To The Nuclear And Outer Plasma Membrane |
| Alternative Antibody Names | Anti-Sulfhydryl Oxidase 2 antibodyAnti-Neuroblastoma-Derived Sulfhydryl Oxidase antibodyAnti-Quiescin Q6-Like Protein 1 antibodyAnti-QSOX2 antibodyAnti-QSCN6L1 antibodyAnti-SOXN antibody |
Information sourced from Uniprot.org
