Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human/Mouse/Rat/Dog |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-Pyruvate dehydrogenase/PDHX (C-Term) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
ELISA-antibody detection limit dilution 1:32000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
PDHX |
Gene ID: |
8050 |
Uniprot ID: |
ODPX_HUMAN |
Immunogen Region: |
C-Term |
Accession Number: |
NP_003468.2; NP_001128496.1; NP_001159630.1 |
Specificity: |
This antibody is expected to recognise all reported isoforms. |
Immunogen Sequence: |
KSFKANLENPIRLA |
Function | Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. |
Protein Name | Pyruvate Dehydrogenase Protein X Component - MitochondrialDihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase ComplexE3-Binding ProteinE3bpLipoyl-Containing Pyruvate Dehydrogenase Complex Component XProx |
Database Links | Reactome: R-HSA-204174Reactome: R-HSA-389661Reactome: R-HSA-5362517Reactome: R-HSA-70268 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-Pyruvate Dehydrogenase Protein X Component - Mitochondrial antibodyAnti-Dihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase Complex antibodyAnti-E3-Binding Protein antibodyAnti-E3bp antibodyAnti-Lipoyl-Containing Pyruvate Dehydrogenase Complex Component X antibodyAnti-Prox antibodyAnti-PDHX antibodyAnti-PDX1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance