| Short Description : | Goat polyclonal antibody anti-Pyruvate dehydrogenase/PDHX (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications: | Pep-ELISA/WB |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 50kDa band observed in Human Pancreas lysate (calculated MW of 54.2kDa according to NP_003468.1). In transfected HEK293 transiently expressing PDHX a band of approx. 50kDa is ob |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PDHX |
| Gene ID: | 8050 |
| Uniprot ID: | ODPX_HUMAN |
| Accession Number: | NP_003468.2; NP_001128496.1; NP_001159630.1 |
| Immunogen Region: | C-Term |
| Immunogen Sequence: | KSFKANLENPIRLA |
| Specificity: | This antibody is expected to recognise all reported isoforms. |
| Function | Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. |
| Protein Name | Pyruvate Dehydrogenase Protein X Component - MitochondrialDihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase ComplexE3-Binding ProteinE3bpLipoyl-Containing Pyruvate Dehydrogenase Complex Component XProx |
| Database Links | Reactome: R-HSA-204174Reactome: R-HSA-5362517Reactome: R-HSA-9861559 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Pyruvate Dehydrogenase Protein X Component - Mitochondrial antibodyAnti-Dihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase Complex antibodyAnti-E3-Binding Protein antibodyAnti-E3bp antibodyAnti-Lipoyl-Containing Pyruvate Dehydrogenase Complex Component X antibodyAnti-Prox antibodyAnti-PDHX antibodyAnti-PDX1 antibody |
Information sourced from Uniprot.org
