Anti-PYGM antibody (743-842) (STJ111685)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PYGM (743-842) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PYGM |
| Gene ID | 5837 |
| Uniprot ID | PYGM_HUMAN |
| Immunogen Region | 743-842 |
| Immunogen Sequence | IEQLSSGFFSPKQPDLFKDI VNMLMHHDRFKVFADYEDYI KCQEKVSALYKNPREWTRMV IRNIATSGKFSSDRTIAQYA REIWGVEPSRQRLPAPDEAI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 743-842 of human PYGM (NP_005600.1). |
Additional Info
| Post Translational Modifications | Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A. |
| Function | Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. |
| Protein Name | Glycogen Phosphorylase - Muscle FormMyophosphorylase |
| Database Links | Reactome: R-HSA-70221 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Glycogen Phosphorylase - Muscle Form antibodyAnti-Myophosphorylase antibodyAnti-PYGM antibody |
Information sourced from Uniprot.org