| Short Description : | Rabbit polyclonal PYCR2 (271-320) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PYCR2 |
| Gene ID: | 29920 |
| Uniprot ID: | P5CR2_HUMAN |
| Immunogen Region: | 271-320 |
| Immunogen Sequence: | MADQEKISPAALKKTLLDRV KLESPTVSTLTPSSPGKLLT RSLALGGKKD |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 271-320 of human PYCR2 (NP_037460.2). |
| Tissue Specificity | Detected in erythrocytes (at protein level). Expressed in fetal brain. |
| Function | Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). |
| Protein Name | Pyrroline-5-Carboxylate Reductase 2P5c Reductase 2P5cr 2 |
| Database Links | Reactome: R-HSA-8964539 |
| Cellular Localisation | CytoplasmMitochondrion |
| Alternative Antibody Names | Anti-Pyrroline-5-Carboxylate Reductase 2 antibodyAnti-P5c Reductase 2 antibodyAnti-P5cr 2 antibodyAnti-PYCR2 antibody |
Information sourced from Uniprot.org
