| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PYCR2 |
| Gene ID: | 29920 |
| Uniprot ID: | P5CR2_HUMAN |
| Immunogen Region: | 271-320 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 271-320 of human PYCR2 (NP_037460.2). |
| Immunogen Sequence: | MADQEKISPAALKKTLLDRV KLESPTVSTLTPSSPGKLLT RSLALGGKKD |
| Tissue Specificity | Detected in erythrocytes (at protein level). Expressed in fetal brain. |
| Function | Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. Involved in cellular response to oxidative stress. |
| Protein Name | Pyrroline-5-Carboxylate Reductase 2P5c Reductase 2P5cr 2 |
| Database Links | Reactome: R-HSA-8964539 |
| Cellular Localisation | CytoplasmMitochondrion |
| Alternative Antibody Names | Anti-Pyrroline-5-Carboxylate Reductase 2 antibodyAnti-P5c Reductase 2 antibodyAnti-P5cr 2 antibodyAnti-PYCR2 antibody |
Information sourced from Uniprot.org