Post Translational Modifications | Farnesylated. Farnesylation is required for membrane targeting and for interaction with RABGGTB. Unfarnesylated forms are redirected to the nucleus and cytosol. |
Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB. |
Protein Name | Protein Tyrosine Phosphatase Type Iva 2Hu-Pp-1Ov-1Ptp(CaaxiiProtein-Tyrosine Phosphatase 4a2Protein-Tyrosine Phosphatase Of Regenerating Liver 2Prl-2 |
Database Links | Reactome: R-HSA-8873719 |
Cellular Localisation | Cell MembraneEarly EndosomeCytoplasm |
Alternative Antibody Names | Anti-Protein Tyrosine Phosphatase Type Iva 2 antibodyAnti-Hu-Pp-1 antibodyAnti-Ov-1 antibodyAnti-Ptp(Caaxii antibodyAnti-Protein-Tyrosine Phosphatase 4a2 antibodyAnti-Protein-Tyrosine Phosphatase Of Regenerating Liver 2 antibodyAnti-Prl-2 antibodyAnti-PTP4A2 antibodyAnti-PRL2 antibodyAnti-PTPCAAX2 antibodyAnti-BM-008 antibody |
Information sourced from Uniprot.org