| Post Translational Modifications | Farnesylated. Farnesylation is required for membrane targeting and for interaction with RABGGTB. Unfarnesylated forms are redirected to the nucleus and cytosol. |
| Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB. |
| Protein Name | Protein Tyrosine Phosphatase Type Iva 2Hu-Pp-1Ov-1Ptp(CaaxiiProtein-Tyrosine Phosphatase 4a2Protein-Tyrosine Phosphatase Of Regenerating Liver 2Prl-2 |
| Database Links | Reactome: R-HSA-8873719 |
| Cellular Localisation | Cell MembraneEarly EndosomeCytoplasm |
| Alternative Protein Names | Protein Tyrosine Phosphatase Type Iva 2 proteinHu-Pp-1 proteinOv-1 proteinPtp(Caaxii proteinProtein-Tyrosine Phosphatase 4a2 proteinProtein-Tyrosine Phosphatase Of Regenerating Liver 2 proteinPrl-2 proteinPTP4A2 proteinPRL2 proteinPTPCAAX2 proteinBM-008 protein |
Information sourced from Uniprot.org