Anti-PTH antibody (20-115) (STJ28409)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PTH (20-115) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PTH |
| Gene ID | 5741 |
| Uniprot ID | PTHY_HUMAN |
| Immunogen Region | 20-115 |
| Immunogen Sequence | LTKSDGKSVKKRSVSEIQLM HNLGKHLNSMERVEWLRKKL QDVHNFVALGAPLAPRDAGS QRPRKKEDNVLVESHEKSLG EADKADVNVLTKAKSQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 20-115 of human Parathyroid Hormone (Parathyroid Hormone (PTH) ) (NP_000306.1). |
Additional Info
| Function | Parathyroid hormone elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Stimulates 1-14C-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. |
| Protein Name | Parathyroid HormonePthParathormoneParathyrin |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Parathyroid Hormone antibodyAnti-Pth antibodyAnti-Parathormone antibodyAnti-Parathyrin antibodyAnti-PTH antibody |
Information sourced from Uniprot.org