| Short Description : | Rabbit polyclonal PTH (20-115) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTH |
| Gene ID: | 5741 |
| Uniprot ID: | PTHY_HUMAN |
| Immunogen Region: | 20-115 |
| Immunogen Sequence: | LTKSDGKSVKKRSVSEIQLM HNLGKHLNSMERVEWLRKKL QDVHNFVALGAPLAPRDAGS QRPRKKEDNVLVESHEKSLG EADKADVNVLTKAKSQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-115 of human Parathyroid Hormone (Parathyroid Hormone (PTH) ) (NP_000306.1). |
| Function | Parathyroid hormone elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Stimulates 1-14C-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. |
| Protein Name | Parathyroid HormonePthParathormoneParathyrin |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Parathyroid Hormone antibodyAnti-Pth antibodyAnti-Parathormone antibodyAnti-Parathyrin antibodyAnti-PTH antibody |
Information sourced from Uniprot.org
