Anti-PRR5 antibody (STJA0008361)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PRR5
General Information
| Short Description | Rabbit polyclonal anti-Proline-rich protein 5 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRR5 |
| Gene ID | 55615 |
| Uniprot ID | PRR5_HUMAN |
| Immunogen | Synthesized peptide derived from human PRR5 |
| Specificity | This antibody detects endogenous levels of PRR5 at Human, Mouse, Rat |
Additional Info
| Function | Associated subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. PRR5 plays an important role in regulation of PDGFRB expression and in modulation of platelet-derived growth factor signaling. May act as a tumor suppressor in breast cancer. |
| Protein Name | Proline-Rich Protein 5Protein Observed With Rictor-1Protor-1 |
| Database Links | Reactome: R-HSA-1257604Reactome: R-HSA-389357Reactome: R-HSA-5218920Reactome: R-HSA-5674400Reactome: R-HSA-6804757Reactome: R-HSA-9856530 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Proline-Rich Protein 5 antibodyAnti-Protein Observed With Rictor-1 antibodyAnti-Protor-1 antibodyAnti-PRR5 antibodyAnti-PROTOR1 antibodyAnti-PP610 antibody |
Information sourced from Uniprot.org