| Host: | Mouse |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Proteinase Inhibitor 9 is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | PI9-17 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | serumfree culture supernatant with 0.7% BSA and 0.1% sodium azide |
| Concentration: | 250 ug/mL |
| Dilution Range: | IHC 1:100WB |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Immunogen: | fl recombinant PI9 |
| Background | The human intracellular serpin proteinase inhibitor 9 (PI9) is the only human protein able to inhibit the activity of the serine protease granzyme B. Granzyme B is expressed by cytotoxic lymphocytes and induces rapid target cell apoptosis. PI9-17 Mab was selected after immunization with full length recombinant PI9 produced in Escherichia coli. No cross reactivity with other, homologous serpins (PI6, PI8 and PAI-2) was observed. |
Information sourced from Uniprot.org