• Western blot analysis of various lysates using PROS1 Rabbit polyclonal antibody (STJ25158) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-PROS1 antibody (405-676) (STJ25158)

SKU:
STJ25158

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PROS1 (405-676) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PROS1
Gene ID: 5627
Uniprot ID: PROS_HUMAN
Immunogen Region: 405-676
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 405-676 of human PROS1 (NP_000304.2).
Immunogen Sequence: MDINKPGPLFKPENGLLETK VYFAGFPRKVESELIKPINP RLDGCIRSWNLMKQGASGIK EIIQEKQNKHCLVTVEKGSY YPGSGIAQFHIDYNNVSSAE GWHVNVTLNIRPSTGTGVML ALVSGNNTVPFAVSLVDSTS EKSQDILLSVENTVIYRIQA LSLCSDQQSHLEFRVNRNNL ELSTPLKIETISHEDLQRQL AVLDKAMKAKVATYLGGLPD VPFSATPVNAFYNGCMEVN
Tissue Specificity Plasma.
Post Translational Modifications The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Function Anticoagulant plasma protein.it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
Protein Name Vitamin K-Dependent Protein S
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-140837
Reactome: R-HSA-140875
Reactome: R-HSA-159740
Reactome: R-HSA-159763
Reactome: R-HSA-159782
Reactome: R-HSA-202733
Reactome: R-HSA-977606
Cellular Localisation Secreted
Alternative Antibody Names Anti-Vitamin K-Dependent Protein S antibody
Anti-PROS1 antibody
Anti-PROS antibody

Information sourced from Uniprot.org

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