Anti-PROS1 antibody (405-676) (STJ25158)

Name: Anti-PROS1 antibody (405-676) (STJ25158)
SKU: STJ25158
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ25158

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Short Description	Rabbit polyclonal PROS1 (405-676) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	PROS1
Gene ID	5627
Uniprot ID	PROS_HUMAN
Immunogen Region	405-676
Immunogen Sequence	MDINKPGPLFKPENGLLETK VYFAGFPRKVESELIKPINP RLDGCIRSWNLMKQGASGIK EIIQEKQNKHCLVTVEKGSY YPGSGIAQFHIDYNNVSSAE GWHVNVTLNIRPSTGTGVML ALVSGNNTVPFAVSLVDSTS EKSQDILLSVENTVIYRIQA LSLCSDQQSHLEFRVNRNNL ELSTPLKIETISHEDLQRQL AVLDKAMKAKVATYLGGLPD VPFSATPVNAFYNGCMEVN
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 405-676 of human PROS1 (NP_000304.2).

Tissue Specificity	Plasma.
Post Translational Modifications	The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Function	Anticoagulant plasma protein.it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
Protein Name	Vitamin K-Dependent Protein S
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-140837 Reactome: R-HSA-140875 Reactome: R-HSA-159740 Reactome: R-HSA-159763 Reactome: R-HSA-159782 Reactome: R-HSA-202733 Reactome: R-HSA-977606
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Vitamin K-Dependent Protein S antibody Anti-PROS1 antibody Anti-PROS antibody

Information sourced from Uniprot.org