Anti-PROK1 antibody (1-50 aa) (STJ196530)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human Prokineticin-1 at the amino acid range 1-50
General Information
| Short Description | Rabbit polyclonal anti-Prokineticin-1 (1-50 aa) for use in IHC and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-200ELISA-Pep 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PROK1 |
| Gene ID | 84432 |
| Uniprot ID | PROK1_HUMAN |
| Immunogen | Synthesized peptide derived from the human Prokineticin-1 at the amino acid range 1-50 |
| Immunogen Region | 1-50 aa |
| Specificity | This antibody detects endogenous levels of human Prokineticin-1 |
Additional Info
| Function | Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. |
| Protein Name | Prokineticin-1Endocrine-Gland-Derived Vascular Endothelial Growth FactorEg-VegfMambakine |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Prokineticin-1 antibodyAnti-Endocrine-Gland-Derived Vascular Endothelial Growth Factor antibodyAnti-Eg-Vegf antibodyAnti-Mambakine antibodyAnti-PROK1 antibodyAnti-UNQ600 antibodyAnti-PRO1186 antibody |
Information sourced from Uniprot.org