| Host: |
Mouse |
| Applications: |
ELISA |
| Reactivity: |
All Species |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Progesterone is suitable for use in ELISA research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
EBS-O-048 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
PBS with 0.02% Sodium Azide. |
| Purification: |
Affinity purified from tissue culture. |
| Concentration: |
Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Dilution Range: |
ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT). |
| Storage Instruction: |
Store for up to 1 year at 2-8°C upon receipt. |
| Gene Symbol: |
PGRMC2 |
| Gene ID: |
10424 |
| Uniprot ID: |
PGRC2_HUMAN |
| Immunogen: |
A BALB/c mouse was immunized with Progesterone-11a-hemisuccinate conjugated to BSA (Progesterone-11a-HMS-BSA). Fusion partner: X63-Ag8-653. |
| Tissue Specificity | Expressed by endometrial glands and stroma (at protein level). Detected in urine (at protein level). |
| Function | Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. May serve as a universal non-classical progesterone receptor in the uterus (Probable). Intracellular heme chaperone required for delivery of labile, or signaling heme, to the nucleus. Plays a role in adipocyte function and systemic glucose homeostasis. In brown fat, which has a high demand for heme, delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1. |
| Protein Name | Membrane-Associated Progesterone Receptor Component 2Progesterone Membrane-Binding ProteinSteroid Receptor Protein Dg6 |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013404Reactome: R-HSA-9013405Reactome: R-HSA-9013408Reactome: R-HSA-9013423Reactome: R-HSA-9707616 |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinNucleus EnvelopeEndoplasmic ReticulumSecreted |
| Alternative Antibody Names | Anti-Membrane-Associated Progesterone Receptor Component 2 antibodyAnti-Progesterone Membrane-Binding Protein antibodyAnti-Steroid Receptor Protein Dg6 antibodyAnti-PGRMC2 antibodyAnti-DG6 antibodyAnti-PMBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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